2. Product
  3. Biology Focused Screening
  4. ID3EAL miRNA Knowledge Panel
Assay Search
  • ID3EAL miRNA Knowledge Panels Workflow

    RNA to Results in 2 hours
    Reliable Data
    Ready-to-Use Kit
    Automated Analysis Template

    RNA to Results in 2 hours
    Using MiRXES’ patented miRNA RT-qPCR technology, the ID3EAL Knowledge Panels can produce results from RNA samples in just 2 hours.

    Reliable Data
    Assays optimized by MIRXES’ proprietary algorithm and wet-lab validated with synthetic miRNA templates and RNA from biological samples.

    Ready-to-Use Kit
    All reagents, including two spike-in RNAs and interplate PCR calibrators, are provided proportionally to maximize convenience and user experience.

    Automated Analysis Template
    An open Excel template is available for automated analysis. The template includes options for expression normalization, data visualization and data integrity checks.
  • Highly curated panel content based on publications

    MiRXES Knowledge Panels are specially curated through intelligent literature review. miRNAs cited in high-impact journals were prioritized and included as panel content.

    Cancer miRNA Panel
    miRNAs are intimately involved in every hallmark of cancer. Detecting miRNA dysregulations could provide insights into cancer pathogenesis, drug response and recurrence.
    The MiRXES ID3EAL Cancer miRNA Knowledge panel consists of 352 miRNAs strongly associated with various cancer types and regulate key onco and tumor suppressor genes and pathways.


    Biofluid miRNA Panel
    miRNAs are selectively and actively secreted by cells as a means of inter-cellular communication. These circulating miRNAs have shown extraordinary stability in biofluids and hold great potential as novel non-invasive biomarkers for disease diagnosis, prognosis and monitoring.
    The MiRXES ID3EAL Biofluid miRNA Knowledge panel consists of 176 miRNAs selected from in-house research of more than 20,000 human serum, plasma and urine specimens in both healthy and pathological conditions.
  • Publication grade representation

    MiRXES automated and open Excel template allows quick data analysis. This includes quality control check on the workflow, expression normalization, simple student's t test across the samples and free to use data representation in minutes

    Boxplot showing miRNAs and their Ct values detected from the bone marrow group. Out of the 176 miRNA targets, 164 miRNAs were detected. A total of 142 miRNAs were determined as positive calls (Ct≤ 33).

    Unsupervised clustering showing global changes in miRNA expression pattern. Distinct miRNA expression profiles were observed as the hfMSCs differentiated into adipose and bone marrow lineage.

    Volcano plot showing ΔΔCt on the x-axis and p-value on the y-axis. Four miRNAs showed statistical significance, with greater than 4-fold change, and were highlighted in red circles.